Dr. Alberto Bianco received his PhD in 1995 from the University of Padova (Italy). As a visiting scientist, he worked at the University of Lausanne during 1992, at the University of Tübingen in 1996–1997 (as an Alexander von Humboldt fellow) and at the University of Padova in 1997–1998. He is currently First Class Research Director at the CNRS in Strasbourg (France). His research interests focus on the design of multifunctional carbon-based nanomaterials (carbon nanotubes, graphene and adamantane) and other 2D materials (hBN, transition metal dichalcogenides) for therapeutic, diagnostic and imaging applications. He is also intereste on the impact of this type of materials on health. He is author and co-author of over 220 papers. He is Associate Editor of Nanotechnology Reviews and in the Advisory Board of Nanomedicine (Lond.) and the Journal of Peptide Science. In 2011 he has been appointed as Editor of Carbon.
Graphene is raising tremendous interest in the biomedical field. Indeed is being explored for many potential medical applications, particularly for cancer treatment, due to its exceptional physicochemical characteristics. In this presentation, I will illustrate the biological impact of few-layer graphene (FLG) on human immune primary cell populations. FLG have a specific impact on monocytes showing neither toxic nor activation effects on the other types of immune cells. Thanks to this intrinsic biological property, FLG was further explored in a therapeutic application towards neoplastic monocytes, obtained from myelomonocytic leukemia patients. FLG have the unique ability to target and successfully boost the necrosis of monocytic cancer cells. Moreover, the comparison between FLG and the common chemotherapeutic drug, etoposide, confirmed the specificity and higher toxicity of graphene on cancer cells. These findings open the way to a possible application of FLG as a specifically targeted tool against monocytic tumour cells.
CGIA supports members to focus on application and industry chain, to keep pace with market development, to guarantee industry interests by involving in policy making and establishing standards, and to build long-term cooperation with up-down stream enterprises all over the world.
E-mail: meeting@c-gia.org
Abstract: Minyang Lu
Sponsor: Wenyang Yang
Media: Liping Wang
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